Introduction: Specific absorption rate (SAR) is crucial for monitoring radiofrequency power absorption during MRI. Although local SAR distribution is usually calculated through numerical simulations, they are impractical during exams, limiting real-time patient-specific SAR assessment. This study confirms the feasibility of deriving in vivo, subject-specific, image-based SAR and 10-g SAR maps directly from MRI data. Methods: Complex B1+ maps were derived by combining a B1+ product (XFL) magnitude sequence with balanced steady-state free precession phase. Anatomical information and tissue masking were obtained from a T1 magnetization-prepared rapid gradient echo sequence. Electrical conductivity maps were generated from balanced steady-state free precession phase. Whole-brain SAR maps were created from MRI data acquired at 3 T using a 32-channel head coil on 2 healthy volunteers. A correction factor was applied to account for underestimation due to reliance on measurable B1+ data. Numerical simulations compared image-based SAR with simulation-based SAR distributions. Results: A multi-slice image-based brain SAR map was obtained in 12 min (9-min acquisition, 3-min SAR reconstruction). In vitro experiments validated B1+ distribution and electrical conductivity values. Calculated electrical conductivities for in vitro and in vivo experiments were within reference ranges. Image-based SAR and 10-g SAR maps showed a distribution similar to simulation-based maps (r = 0.5) after correction. Conclusions: This study shows the feasibility of inline, subject-specific SAR and 10-g SAR maps from standard brain clinical sequences. Image-based SAR maps can be a practical alternative during MRI exams when simulations are not feasible.

Feasibility study of subject‐specific, brain specific‐absorption‐rate maps retrieved from MRI data / Martinez, Jessica A.; Zanovello, Umberto; Arduino, Alessandro; Hu, Houchun Harry; Moulin, Kevin; Ogier, Stephen E.; Bottauscio, Oriano; Zilberti, Luca; Keenan, Kathryn E.. - In: MAGNETIC RESONANCE IN MEDICINE. - ISSN 0740-3194. - 94:3(2025), pp. 1136-1151. [10.1002/mrm.30547]

Feasibility study of subject‐specific, brain specific‐absorption‐rate maps retrieved from MRI data

Zanovello, Umberto;Arduino, Alessandro;Bottauscio, Oriano;Zilberti, Luca;
2025

Abstract

Introduction: Specific absorption rate (SAR) is crucial for monitoring radiofrequency power absorption during MRI. Although local SAR distribution is usually calculated through numerical simulations, they are impractical during exams, limiting real-time patient-specific SAR assessment. This study confirms the feasibility of deriving in vivo, subject-specific, image-based SAR and 10-g SAR maps directly from MRI data. Methods: Complex B1+ maps were derived by combining a B1+ product (XFL) magnitude sequence with balanced steady-state free precession phase. Anatomical information and tissue masking were obtained from a T1 magnetization-prepared rapid gradient echo sequence. Electrical conductivity maps were generated from balanced steady-state free precession phase. Whole-brain SAR maps were created from MRI data acquired at 3 T using a 32-channel head coil on 2 healthy volunteers. A correction factor was applied to account for underestimation due to reliance on measurable B1+ data. Numerical simulations compared image-based SAR with simulation-based SAR distributions. Results: A multi-slice image-based brain SAR map was obtained in 12 min (9-min acquisition, 3-min SAR reconstruction). In vitro experiments validated B1+ distribution and electrical conductivity values. Calculated electrical conductivities for in vitro and in vivo experiments were within reference ranges. Image-based SAR and 10-g SAR maps showed a distribution similar to simulation-based maps (r = 0.5) after correction. Conclusions: This study shows the feasibility of inline, subject-specific SAR and 10-g SAR maps from standard brain clinical sequences. Image-based SAR maps can be a practical alternative during MRI exams when simulations are not feasible.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11696/87520
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