Calcium phosphate glass based single-mode and multi-mode bioresorbable optical fibers were in-house manufactured. Ex-vivo studies were then conducted to test the suitability of these fibers for time gated diffuse optics spectroscopy, photodynamic therapy and diffuse correlation spectroscopy applications which can be respectively employed for the diagnosis, treatment, and monitoring of malignant tissues. The results demonstrated the potential of calcium phosphate glass-based fiber optic devices towards the realization of an implantable multi-functional class of devices with functionalities ranging from cancer detection to monitoring of the healing process all integrated into a single bioresorbable platform. Acknowledgement: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 860185.
Bioresorbable multifunctional fiber-optic devices for theranostic and monitoring of tumor / Pandayil, Jawad; Giovanna Boetti, Nadia; Pugliese, Diego; Cortese, Lorenzo; Damagatla, Sai Vamshi Krishna; Durduran, Turgut; Pifferi, Antonio; Janner, Davide. - PC12835:(2024). (Intervento presentato al convegno SPIE BiOS, 2024, Photonics West tenutosi a San Francisco, California (United States) nel 27 January - 1 February 2024) [10.1117/12.3002672].
Bioresorbable multifunctional fiber-optic devices for theranostic and monitoring of tumor
Pugliese, Diego;
2024
Abstract
Calcium phosphate glass based single-mode and multi-mode bioresorbable optical fibers were in-house manufactured. Ex-vivo studies were then conducted to test the suitability of these fibers for time gated diffuse optics spectroscopy, photodynamic therapy and diffuse correlation spectroscopy applications which can be respectively employed for the diagnosis, treatment, and monitoring of malignant tissues. The results demonstrated the potential of calcium phosphate glass-based fiber optic devices towards the realization of an implantable multi-functional class of devices with functionalities ranging from cancer detection to monitoring of the healing process all integrated into a single bioresorbable platform. Acknowledgement: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 860185.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
