Studying the depolarization rate of light emerging from a turbid medium holds promise for the non-invasive characterization of its single-scattering properties, with relevant application in the quality analysis of different specimens or for diagnostic purposes in the biomedical field, to name a few. However, irrespective of sample geometry, the dynamics of light depolarization takes place on a time scale of few ps, which is too fast for traditional detection methods. Here, we present experimental results on the time-domain evolution of the depolarization ratio of light that is diffusely reflected from a scattering medium, using linearly polarized fs pulses in an all-optical gating scheme. Time-resolved reflectance curves are recorded in the parallel and perpendicular polarization channels relative to the illumination beam, granting direct access to the depolarization rate. We demonstrate our experimental approach on a lipid emulsion, fitting the data with a polarized Monte Carlo simulation to retrieve the average particle size and scattering asymmetry factor using just two time-domain reflectance measurements in a semi-infinite geometry.

Time-resolved depolarization analysis of back-scattered light / Pini, Ernesto; Martelli, Fabrizio; Wiersma, Diederik; Gatto, Alexander; Schäfer, Henrik; Pattelli, Lorenzo. - In: PROGRESS IN BIOMEDICAL OPTICS AND IMAGING. - ISSN 1605-7422. - 12845:(2024). (Intervento presentato al convegno SPIE BIOS 2024 tenutosi a San Francisco, California, United States nel 27-28/01/2024) [10.1117/12.3001002].

Time-resolved depolarization analysis of back-scattered light

Wiersma, Diederik;Pattelli, Lorenzo
2024

Abstract

Studying the depolarization rate of light emerging from a turbid medium holds promise for the non-invasive characterization of its single-scattering properties, with relevant application in the quality analysis of different specimens or for diagnostic purposes in the biomedical field, to name a few. However, irrespective of sample geometry, the dynamics of light depolarization takes place on a time scale of few ps, which is too fast for traditional detection methods. Here, we present experimental results on the time-domain evolution of the depolarization ratio of light that is diffusely reflected from a scattering medium, using linearly polarized fs pulses in an all-optical gating scheme. Time-resolved reflectance curves are recorded in the parallel and perpendicular polarization channels relative to the illumination beam, granting direct access to the depolarization rate. We demonstrate our experimental approach on a lipid emulsion, fitting the data with a polarized Monte Carlo simulation to retrieve the average particle size and scattering asymmetry factor using just two time-domain reflectance measurements in a semi-infinite geometry.
2024
SPIE BIOS 2024
27-28/01/2024
San Francisco, California, United States
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11696/80719
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