We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.

Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber / Podrazky, O.; Peterka, P.; Vytykacova, S.; Probostova, J.; Kunes, M.; Lyutakov, O.; Ceci-Ginistrelli, E.; Pugliese, D.; Boetti, N. G.; Janner, D.; Milanese, D.. - In: PROGRESS IN BIOMEDICAL OPTICS AND IMAGING. - ISSN 1605-7422. - 10488:(2018). (Intervento presentato al convegno Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018 tenutosi a usa nel 2018) [10.1117/12.2285148].

Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber

Pugliese D.;
2018

Abstract

We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.
2018
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018
2018
usa
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11696/77411
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