Uncertainties affecting diagnostic tests for Alzheimer's disease (AD) are discussed from a bio-metrological point of view. The estimated sensitivity and specificity of a test are analyzed in a numerical example as predictors of its performance in real cases application. Current trends in molecular diagnostic research are outlined in view of reducing the effects of uncertainty factors involved in AD diagnosis.

Diagnostic uncertainty in Alzheimer's disease : A bio-metrology perspective addressed to microRNA-based biomarkers / D'Errico, G. E.; Divieto, C.. - (2018). (Intervento presentato al convegno 2018 IEEE International Symposium on Medical Measurements and Applications) [10.1109/MeMeA.2018.8438799].

Diagnostic uncertainty in Alzheimer's disease : A bio-metrology perspective addressed to microRNA-based biomarkers

D'Errico, G. E.;Divieto, C.
2018

Abstract

Uncertainties affecting diagnostic tests for Alzheimer's disease (AD) are discussed from a bio-metrological point of view. The estimated sensitivity and specificity of a test are analyzed in a numerical example as predictors of its performance in real cases application. Current trends in molecular diagnostic research are outlined in view of reducing the effects of uncertainty factors involved in AD diagnosis.
2018
2018 IEEE International Symposium on Medical Measurements and Applications
restricted
File in questo prodotto:
File Dimensione Formato  
08438799.pdf

solo utenti autorizzati

Descrizione: Articolo principale
Tipologia: accepted manuscript (author’s post-print)
Licenza: Non Pubblico - Accesso privato/ristretto
Dimensione 2.54 MB
Formato Adobe PDF
2.54 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11696/59993
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 0
social impact