In this article, we described click chemistry methodology for the incorporation of biocompatible polymer chains to Magnetite nanoparticles (NPs). We used a reduction co-precipitation method to obtain Fe 3O 4 particles in aqueous solution. As a next step, magnetic NPs surface were modified by a silanization reaction with (3-bromopropyl)trimethoxysilane in order to introduce bromine groups on the particles surface which were converted to azide groups by the reaction with sodium azide. Acetylene functionalized poly(ethylene glycol) (a-PEG) and poly(ε-caprolactone) (a-PCL) were synthesized and grafted onto the surface of azide functionalized NPs via "click" reaction to obtain magnetic NPs. Success of the different functionalization processes at different stages was studied using Fourier Transform infrared spectroscopy (FTIR). The morphologies of magnetic NPs were further investigated by transmission electron microscopy (TEM). The magnetization and superparamagnetic behavior of naked Fe 3O 4 NPs and coated NPs at room temperature was investigated by the measurement of hysteresis curves using a Vibrating Sample Magnetometer (VSM).

Polymer grafting onto magnetite nanoparticles by "click" reaction / Amici, J; Kahveci, Mu; Allia, P; Tiberto, PAOLA MARIA; Yagci, Y; Sangermano, M.. - In: JOURNAL OF MATERIALS SCIENCE. - ISSN 0022-2461. - 47:1(2012), pp. 412-419. [10.1007/s10853-011-5814-z]

Polymer grafting onto magnetite nanoparticles by "click" reaction

TIBERTO, PAOLA MARIA;
2012

Abstract

In this article, we described click chemistry methodology for the incorporation of biocompatible polymer chains to Magnetite nanoparticles (NPs). We used a reduction co-precipitation method to obtain Fe 3O 4 particles in aqueous solution. As a next step, magnetic NPs surface were modified by a silanization reaction with (3-bromopropyl)trimethoxysilane in order to introduce bromine groups on the particles surface which were converted to azide groups by the reaction with sodium azide. Acetylene functionalized poly(ethylene glycol) (a-PEG) and poly(ε-caprolactone) (a-PCL) were synthesized and grafted onto the surface of azide functionalized NPs via "click" reaction to obtain magnetic NPs. Success of the different functionalization processes at different stages was studied using Fourier Transform infrared spectroscopy (FTIR). The morphologies of magnetic NPs were further investigated by transmission electron microscopy (TEM). The magnetization and superparamagnetic behavior of naked Fe 3O 4 NPs and coated NPs at room temperature was investigated by the measurement of hysteresis curves using a Vibrating Sample Magnetometer (VSM).
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11696/29256
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 25
  • ???jsp.display-item.citation.isi??? 25
social impact